A recent study in the UK explored how controlled inhalation of THC-dominant cannabis flower affects people with post-traumatic stress disorder (PTSD). PTSD is a mental health condition affecting about 4% of the UK population, and it includes symptoms like intrusive memories, avoidance behaviors, mood changes, and altered reactions. Researchers wanted to see if THC, a compound in cannabis, could help manage these symptoms. They analyzed data from the UK’s T21 registry, which collects health information from patients prescribed medical cannabis. To be included, participants had to have a confirmed PTSD diagnosis, complete health surveys before and after treatment, and use a THC-dominant cannabis product.

The study involved 58 participants, most of whom were men around 39 years old with prior cannabis experience. They completed health surveys at the start, three months, and six months after beginning cannabis treatment. By the three-month mark, patients reported major improvements in their overall health, mood, and sleep, though the quality-of-life measure didn’t reach statistical significance. These improvements were not only maintained but, for some patients, even grew by the six-month check-in. Notably, patients reported fewer intrusive memories, better mood control, and reduced reactivity, all without any reported negative side effects.

Over six months, the participants’ symptom severity dropped by an average of 16.8 points, showing that the cannabis treatment effectively reduced PTSD symptoms. The study suggests that THC-dominant cannabis can be a beneficial option for PTSD management, particularly for patients who have not found relief through conventional medications. Since 2018, doctors in the UK have been able to prescribe medical cannabis to patients who don’t respond well to standard treatments, giving PTSD patients a new option for symptom relief.

While this study shows promising results, the researchers emphasized the need for further research, especially on the long-term effects of THC use in people new to cannabis. Other studies from the UK Medical Cannabis Registry also report that cannabis-based products are effective for managing chronic pain, anxiety, depression, and other conditions. This growing body of evidence points to the potential of cannabis to support patients with various chronic health issues, though more research is needed to understand its full impact.